Publications 2009

[Molecular diagnosis of malignant lymphomas]

Holte H, Kvaløy S, Delabie J, Trøen G, Smeland EB
Tidsskr Nor Laegeforen, (2009) 129 (22), 2352-6

PMID: 19935935

Array-based DNA methylation profiling in follicular lymphoma

O’Riain C, O’Shea DM, Yang Y, Le Dieu R, Gribben JG, Summers K, Yeboah-Afari J, Bhaw-Rosun L, Fleischmann C, Mein CA, Crook T, Smith P, Kelly G, Rosenwald A, Ott G, Campo E, Rimsza LM, Smeland EB, Chan WC, Johnson N, Gascoyne RD, Reimer S, Braziel RM, Wright GW, Staudt LM, Lister TA, Fitzgibbon J.
Leukemia, (2009) 23 (10), 1858-66

PMID: 19587707

Functional glutathione S-transferase (GST) genotypes among testicular germ cell tumor (TGCT) survivors: associations with primary and post-chemotherapy tumor histology.

Kraggerud SM , Oldenburg J , Berg M , Alnæs GIG4, Kristensen VN, Fosså SD, Lothe RA.
Pharmacogenetics and Genomics, 2009, 19:751-759

PMID: 19741569

Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion.

Houot R, Goldstein MJ, Kohrt HE, Myklebust JH, Alizadeh AA, Lin JT, Irish JM, Torchia JA, Kolstad A, Chen L, Levy R.
Blood. 2009 Oct 15;114(16):3431-8. Epub 2009 Jul 29.

PMID: 19641184

A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patients.

Gentles AJ, Alizadeh AA, Lee SI, Myklebust JH, Shachaf CM, Shahbaba B, Levy R, Koller D, Plevritis SK.
Blood. 2009 Oct 8;114(15):3158-66. Epub 2009 Jul 27.

PMID: 19636063

Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101.

Leithe E, Kjenseth A, Sirnes S, Stenmark H, Brech A, Rivedal E.
J Cell Sci. 2009 Nov 1;122(Pt 21):3883-93. Epub 2009 Oct 6.

PMID: 19808888

Identification of p53 as a strong predictor of survival for patients with malignant peripheral nerve sheath tumors.

Brekke HR, Kolberg M, Skotheim RI, Hall KS, Bjerkehagen B, Risberg B, Domanski HA, Mandahl N, Liestøl K, Smeland S, Danielsen HE, Mertens F, Lothe RA.
Neuro Oncol. 2009 Oct;11(5):514-28. Epub 2009 Jan 30.

PMID: 19182148

Large scale genomic instability as an additive prognostic marker in early prostate cancer.

Pretorius ME, Waehre H, Abeler VM, Davidson B, Vlatkovic L, Lothe RA, Giercksky KE, Danielsen HE.
Cell Oncol. 2009;31(4):251-9.

PMID: 19633362

Large-scale genomic instability in colon adenocarcinomas and correlation with patient outcome.

Bondi J, Pretorius M, Bukholm I, Danielsen H.
APMIS. 2009 Oct;117(10):730-6.

PMID: 19775341

Sorting nexin 8 regulates endosome-to-Golgi transport.

Dyve AB, Bergan J, Utskarpen A, Sandvig K.
Biochem Biophys Res Commun. 2009 Dec 4;390(1):109-14. Epub 2009 Sep 24.

PMID: 19782049

Beta-catenin expression in uterine sarcomas and its relation to clinicopathological parameters.

Kildal W, Pradhan M, Abeler VM, Kristensen GB, Danielsen HE.
Eur J Cancer. 2009 Sep;45(13):2412-7. Epub 2009 Jul 20.

PMID: 19622417

Seeing is believing.

Stenmark H.
Nat Rev Mol Cell Biol. 2009 Sep;10(9):582.

PMID: 19702012

The pluripotency transcription factor Krüppel-like factor 4 is strongly expressed in intratubular germ cell neoplasia unclassified and seminoma.

Godmann M, Gashaw I, Eildermann K, Schweyer S, Bergmann M, Skotheim RI, Behr R.
Mol Hum Reprod. 2009, 15:479-488

PMID: 19505997

Rab GTPases as coordinators of vesicle traffic.

Stenmark H.
Nat Rev Mol Cell Biol. 2009 Aug;10(8):513-25. Epub 2009 Jul 15.

PMID: 19603039

Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane.

Zakrzewska M, Zhen Y, Wiedlocha A, Olsnes S, Wesche J.
Biochemistry. 2009 Aug 4;48(30):7209-18.

PMID: 19558187

TPD52, a candidate gene from genomic studies, is overexpressed in testicular germ cell tumours.

Alagaratnam S, Hardy JR, Lothe RA, Skotheim RI, Byrne JA.
Mol Cell Endocrinol, 306: 75-80, 2009.

PMID: 19041365

Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants.

Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D.
J Cell Sci. 2009 Jul 15;122(Pt 14):2413-23.

PMID: 19571114

Increased protein stability of FGF1 can compensate for its reduced affinity for heparin.

Zakrzewska M, Wiedlocha A, Szlachcic A, Krowarsch D, Otlewski J, Olsnes S.
J Biol Chem. 2009 Sep 11;284(37):25388-403. Epub 2009 Jul 2.

PMID: 19574212

How do ESCRT proteins control autophagy?

Rusten TE, Stenmark H.
J Cell Sci. 2009 Jul 1;122(Pt 13):2179-83.

PMID: 19535733

Novel mutations of the suppressor gene PTEN in colorectal carcinomas stratified by microsatellite instability- and TP53 mutation.

Danielsen SA, Lind GE, Bjørnslett M, Meling GI, Rognum TO, Heim S, Lothe RA.
Hum Mutat. 2009 Jun;30(6):1023.

PMID: 18781614

Quantum dot bioconjugates: Uptake into cells and induction of changes in normal cellular transport.

Iversen TG, Frerker N, and Sandvig K.
Progr. Biomed. Optics and imaging. 2009 vol. 10, No 29. 7189, 1-9.

ISSN 1605-7422

Gross genomic alterations differ between serous borderline tumors and serous adenocarcinomas–an image cytometric DNA ploidy analysis of 307 cases with histogenetic implications.

Pradhan M, Davidson B, Tropé CG, Danielsen HE, Abeler VM, Risberg B.
Virchows Arch. 2009 Jun;454(6):677-83. Epub 2009 May 8.

PMID: 19421773

The prognostic value of DNA ploidy in a total population of uterine sarcomas.

Kildal W, Abeler VM, Kristensen GB, Jenstad M, Thoresen SØ, Danielsen HE.
Ann Oncol. 2009 Jun;20(6):1037-41. Epub 2009 Feb 6.

PMID: 19201782

SNX4 in complex with clathrin and dynein: implications for endosome movement.

Skånland SS, Wälchli S, Brech A, Sandvig K.
PLoS One. 2009 Jun 16;4(6):e5935.

PMID: 19529763

Endocytosis and intracellular transport of FGF1 and the FGF receptors.

Haugsten EM.
Norsk Farmaceutisk Tidsskrift, 6/2009, 21-22. (in Norwegian)

Link to article in NFT

Autophagy in tumour suppression and promotion.

Brech A, Ahlquist T, Lothe RA, Stenmark H.
Mol Oncol. 2009 Aug;3(4):366-75. Epub 2009 Jun 6.

PMID: 19559660

ESCRT proteins in physiology and disease.

Stuffers S, Brech A, Stenmark H.
Exp Cell Res. 2009 May 15;315(9):1619-26. Epub 2008 Oct 28.

PMID: 19013455

Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin.

Raa H, Grimmer S, Schwudke D, Bergan J, Wälchli S, Skotland T, Shevchenko A, Sandvig K.
Traffic. 2009 Jul;10(7):868-82. Epub 2009 May 6.

PMID: 19453975

Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells.

Kaiser E, Pust S, Kroll C, Barth H.
Cell Microbiol. 2009, 11(5), 780-795

PMID: 19159389

Interplay between PKC and the MAP kinase pathways in connexin43 phosphorylation and inhibition of gap junction intercellular communication.

Sirnes S, Kjenseth A, Leithe E and Rivedal E.
Biochem. Biophys. Res. Commun., 382: 41-45, 2009.

PMID: 19258009

Predicting helix-helix interactions from residue contacts in membrane proteins.

Lo A, Chiu YY, Rodland EA, Lyu PC, Sung TY, Hsu WL.
Bioinformatics 2009, Apr 15, 25; 996-1003. Epub 2009 Feb 25.

PMID: 19244388

Multivesicular endosome biogenesis in the absence of ESCRTs.

Stuffers S, Sem Wegner C, Stenmark H, Brech A.
Traffic. 2009 Jul;10(7):925-37. Epub 2009 Apr 10.

PMID: 19490536

Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy.

Nezis IP, Lamark T, Velentzas AD, Rusten TE, Bjørkøy G, Johansen T, Papassideri IS, Stravopodis DJ, Margaritis LH, Stenmark H, Brech A.
Autophagy. 2009 Apr;5(3):298-302. Epub 2009 Apr 19.

PMID: 19066465

Germline and somatic NF1 mutations in sporadic and NF1-associated malignant peripheral nerve sheath tumours.

Bottillo I, Ahlquist T, Brekke H, Danielsen SA, van den Berg E, Mertens F, Lothe RA, Dallapiccola B.
J Pathol. 2009 Apr;217(5):693-701.

PMID: 19142971

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins.

Raiborg C, Stenmark H.
Nature. 2009 Mar 26;458(7237):445-52.

PMID: 19325624

Characterization of clathrin and Syk interaction upon Shiga toxin binding.

Wälchli S, Aasheim HC, Skånland SS, Spilsberg B, Torgersen ML, Rosendal KR, Sandvig K.
Cell Signal. 2009 Jul;21(7):1161-8. Epub 2009 Mar 13.

PMID: 19289168

The role of ESCRT proteins in attenuation of cell signalling.

Rodahl LM, Stuffers S, Lobert VH, Stenmark H.
Biochem Soc Trans. 2009 Feb;37(Pt 1):137-42.

PMID: 19143618

Monitoring autophagic degradation of p62/SQSTM1.

Bjørkøy G, Lamark T, Pankiv S, Øvervatn A, Brech A, Johansen T.
Methods Enzymol. 2009;452:181-97.

PMID: 19200883

Uterine sarcomas in Norway. A histopathological and prognostic survey of a total population from 1970 to 2000 including 419 patients.

Abeler VM, Røyne O, Thoresen S, Danielsen HE, Nesland JM, Kristensen GB.
Histopathology. 2009 Feb;54(3):355-64.

PMID: 19236512

Reverse painting of microdissected chromosome 19 markers in ovarian carcinoma identifies a complex rearrangement map.

Micci F, Weimer J, Haugom L, Skotheim RI, Grunewald R, Abeler VM, Silins I, Lothe RA, Trope C, Arnold N, Heim S.
Genes Chromosomes Cancer, 48:184-193, 2009.

PMID: 18973136

Disruption of Vps4 and JNK function in Drosophila causes tumour growth.

Rodahl LM, Haglund K, Sem-Jacobsen C, Wendler F, Vincent JP, Lindmo K, Rusten TE, Stenmark H.
PLoS One. 2009;4(2):e4354. Epub 2009 Feb 4.

PMID: 19194501

Large-scale inference of the point mutational spectrum in human segmental duplications.

Nakken S, Rodland EA, Rognes T, Hovig, E.
BMC Genomics. 2009 Jan 22;10:43.

PMID: 19161616

Beta-arrestins attenuate p38 mediated endosome to Golgi transport.

Skånland SS, Wälchli S, Sandvig K.
Cell Microbiol. 2009 Jan 21.

PMID: 19159388

A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysis.

Skotheim RI, Thomassen GO, Eken M, Lind GE, Micci F, Ribeiro FR, Cerveira N, Teixeira MR, Heim S, Rognes T, Lothe RA.
Mol Cancer. 2009 Jan 19;8:5.

PMID: 19152679

Ligand-specific induction of endocytosis in taste receptor cells.

Døving KB, Sandvig K, Kasumyan A.
J Exp Biol. 2009 Jan;212(Pt 1):42-9.

PMID: 19088209

Structure of a highly stable mutant of human fibroblast growth factor 1.

Szlachcic A, Zakrzewska M, Krowarsch D, Os V, Helland R, Smalås AO, Otlewski J.
Acta Crystallogr D Biol Crystallogr. 2009 Jan;65(Pt 1):67-73. Epub 2008 Dec 18.

PMID: 19153468

ESCRTing membrane deformation.

Malerød L, Stenmark H.
Cell. 2009 Jan 9;136(1):15-7.

PMID: 19135881