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In the August 23 issue of Journal of Cell Biology (impact factor 9.57), published on-line August 16, Ioannis Nezis and his colleagues in Harald Stenmark’s group in the Centre for Cancer Biomedicine and Institute for Cancer Research reveal a mechanistic link between autophagy and programmed cell death.
Autophagy, a cellular process that involves lysosomal […]
Edgar Rivedal from the Department of Cancer Prevention headed by Ragnhild A. Lothe at the Institute for Cancer Research, is newly appointed Chairperson of the Scientifc Council at the International Agency for Research on Cancer (IARC).
The Scientific Council consists of highly qualified scientists, selected on the basis of their technical competence in cancer research […]
In the July 2010 issue of Developmental Cell (impact factor 13.36), PhD student Viola Lobert and her co-workers in Harald Stenmark´s group at the Centre for Cancer Biomedicine, Institute for Cancer Research, demonstrate an unexpected importance of integrin degradation in cell migration.
Integrins are heterodimeric membrane proteins that form contacts between cytosolic cytoskeletal components and […]
At the 2010 FEBS Congress in Gothenburg, Harald Stenmark from the Centre for Cancer Biomedicine and the Institute for Cancer Research was awarded the Sir Hans Krebs Medal.
This medal is awarded annually by the Federation of European Biochemical Societies for “outstanding achievements in Biochemistry and Molecular Biology or related sciences”. Recent awardees include Nobel laureates […]
Shiga toxin binds to the glycosphingolipid Gb3, which has been reported to be highly expressed in many types of cancer.
An updated overview of the published reports on overexpression in human cancers is provided, and the possibility of utilizing Shiga toxin or its binding unit coupled to therapeutic compounds or contrast agents in targeted cancer therapy […]
Kirsten Sandvig from the Department of Biochemistry at the Institute for Cancer Research has been elected as a Fellow of the American Academy of Microbiology due to her work with bacterial toxins.
The Fellows are elected in recognition of their records of scientific achievement, and Sandvig is the third Norwegian to receive this honour from the […]
Kaisa Haglund, project leader in Harald Stenmark´s group at the Centre for Cancer Biomedicine, has recently identified a novel regulator of cytokinesis, the final stage of the cell division process.
In the June 2010 issue of Current Biology (published on-line 5 May), Haglund and her co-workers show that Cindr, the Drosophila homologue of mammalian CIN85 and […]
A recent article from Harald Stenmark’s group published in Nature Cell Biology has attracted considerable attention. The paper is entitled “PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody” and is first-authored by Antonia Sagona.
Now the popular Norwegian research web site “forskning.no” has written an article about the findings under the headline “Strict […]
MD Yan Zhen defended her PhD thesis entitled “Intracellular trafficking and signaling of fibroblast growth factor 1 and its receptor” on Friday 23 April at 10.15 hrs.
She gave her trial lecture on the subject “Challenges and opportunities with kinases as target for cancer therapy” on Thursday 22 April at 15.15 hrs. Both events took place […]
The Norwegian Cancer Society has decided to focus on one research project each month, and the project obtaining attention in March 2010 is directed by CCB group leader Prof. Kirsten Sandvig.
Sandvig’s research has been focused upon in an article published on the web site of the Norwegian Cancer Society entitled “The weapon must be fine-tuned […]
The South-Eastern Norway Regional Health Authority (Helse Sør-Øst) aims to profile ongoing excellent research in the region by calling special attention to a “Researcher of the month” – a prize that was introduced in January 2010.
The third researcher to receive this honor is CCB Director Harald Stenmark from the Department of Biochemistry at Oslo University […]
PhD student Antonia Sagona and her co-workers in Harald Stenmark´s group at the Centre for Cancer Biomedicine, Institute for Cancer Research, have uncovered a new functional mechanism for a known tumour suppressor, the class III phosphatidylinositol 3-kinase (PI3K-III), a protein complex that mediates formation of the membrane lipid, phosphatidylinositol 3-phosphate (PtdIns3P).
Sagona and her co-workers noticed […]
The Molecular Genetics group at the Department of Cancer Prevention, headed by Ragnhild A. Lothe, has recently published a translational research paper in the highly rated “Journal of Clinical Oncology” (journal impact factor 17.2). The article entitled Genomic Changes in Chromosomes 10, 16, and X in Malignant Peripheral Nerve Sheath Tumors Identify a High-Risk Patient […]
PhD student Catherine Sem Wegner and her colleagues in Andreas Brechs project group at CCB, Department of Biochemistry, Institute for Cancer Research, have recently published an article that was selected for the cover of “Histochemistry and Cell Biology”.
The article is a confocal and electron microscopic characterisation of giant endosomes that are induced by a mutant […]
PhD student Sigrid Bratlie Thoresen received the 2nd poster prize at the recent Winter meeting of the Norwegian Biochemical Society. The title of her poster was “Differential roles of the PI3K class III complex subunits in receptor/ligand degradation and cytokinesis”.